Solitary pulmonary nodule: Increasing diagnosis and accuracy of biopsy by biparametric MR imaging

© 2018 Indian Chest Society | Published by Wolters Kluwer Medknow tumors; significant proportions of signal intensity originates from intravascular space.[7] In malignant tumors with enlarged cells, conspicuous nuclei and reduction of the extracellular matrix, water diffusion is restricted due to tissue cellularity with cell membrane integrity and scarce extracellular spaces, resulting in a decrease of the apparent diffusion coefficient (ADC) value. Neoplastic pulmonary lesions generally have restricted diffusion with lower ADCs and so appear hypointense on ADC maps but hyperintense on the DW, high b-value image.[8,9]